Chase takes on a patient, Moira, who is a cloistered nun on the verge of making her life-changing vows, and through the treatment process, he and Moira form a unique connection that tests their faith and reason. But when Moira's condition worsens and requires a risky surgery, Chase's judgment is compromised. Meanwhile, House and Taub try to remain one step ahead of each other's pranks.

Cast: Hugh Laurie, Omar Epps, Robert Sean Leonard, Jesse Spencer, Peter Jacobson, Odette Annable, Charlyne Yi, Terrence Beasor, Liz Benoit, Bobbin Bergstrom, Kandis Erickson, Jessica Luza, Julie Mond, Valeri Ross, Josh Waters