Pilgrims are flooding to Rome for the Jubilee year celebration, but Catherina Sforza has a plan to ruin Alexander's lucrative festival. Meanwhile, Lucrezia senses a change in newly crowned Frederigo and realizes that she is under constant watch from the royal guard. A plot to deceive the Borgia family is uncovered by Lucrezia, Cesare and Micheletto.

Cast: Jeremy Irons, François Arnaud, Holliday Grainger, Sean Harris, Thure Lindhardt, Gina McKee, Peter Sullivan, Charlie Carrick, Sebastian De Souza, Cyron Melville, Peter Stebbings, Brendan Cowell, Kevin Griffiths, Robert Gogo-Fawcett, Noah Silver