The mysterious Mrs. X tasks the sexy - and dangerous - Sophie to cause Jim and George to fall under her spell and make them do whatever she wants them to - which could place Jim's marriage in jeopardy. Meanwhile, Stephanie must decide whether or not to inject a patient with the trilsettum serum and risk turning him into a super in order to retain Dr. King's trust, and Daphne's boyfriend, Chris, begins to have suspicions about the Powell family's abilities.

Cast: Michael Chiklis, Julie Benz, Kay Panabaker, Jimmy Bennett, Autumn Reeser, Romany Malco, Stephen Collins, Josh Stewart, Eric Balfour, Melody Butiu, Corey Michael Eubanks, Randy Evans, Jeremy Guskin, Holly Hannula, Tricia Helfer