The Powells must join together to save JJ, who's been kidnapped, courtesy of Mrs. X and forced to solve an enigma that could lead to the permanence of the trilsettum's effects. Meanwhile, Joshua reconnects with Katie and discovers that he's about to become a father, and George's fate hangs in the balance as a prisoner aboard a plane that's quickly spiraling out of control and about to crash.

Cast: Michael Chiklis, Julie Benz, Kay Panabaker, Jimmy Bennett, Autumn Reeser, Romany Malco, Guillermo Díaz, Jason Antoon, Lucy Lawless, Stephen Collins, Rebecca Mader, Josh Stewart