Returning to Florence, an uninspired Leonardo accepts to paint the portrait of Lisa Gherardini, that will become the Monna Lisa. After failing to repair his relationship with Caterina, Leonardo goes to Imola, where he receives much praise from his employer, Cesare Borgia.

Cast: Aidan Turner, Matilda De Angelis, Carlos Cuevas, Robin Renucci, Claudio Castrogiovanni, Max Bennett, Corrado Invernizzi, Freddie Highmore, Lorenzo Adorni, Tommaso Basili, Francesca Chillemi, Davide Iacopini, Maria Vera Ratti, Alfie Rigby