Peter Parker must find a way to stop Doctor Octopus and the Superior Sinister Six from destroying all of the heroes in New York and taking over the world.

Cast: Drake Bell, Diedrich Bader, Eric Bauza, Tom Kenny, Matt Lanter, Misty Lee, Chi McBride, Adrian Pasdar, Scott Porter, Daryl Sabara, Roger Craig Smith, Fred Tatasciore, Steven Weber