When Chuck calls Gabrielle, Susan and Lynette individually for questioning about the disappearance - and possible murder - of Alejandro, inciting panic, and Bree's life begins to spiral into despair when her friends abandon her after they blame her for scorning Chuck and causing him to take out his revenge on them. Meanwhile, Lynette asks a favor of Tom that could ruin his relationship with Jane (guest star Andrea Parker), and Susan is made a once-in-a-lifetime proposition to become a real artist.

Cast: Teri Hatcher, Felicity Huffman, Marcia Cross, Eva Longoria, Vanessa Williams, Ricardo Chavira, Doug Savant, Jonathan Cake, Madison De La Garza, Brenda Strong, James Denton, Charles Mesure, J.J. Boone, Charles Carpenter, Jennifer Cortese