Sheldon and Amy's super asymmetry theory is proven by two physicists, Dr. Pemberton and Dr. Campbell from Chicago, who then try to kick Amy off the Nobel nomination. Also, Bernadette has a big success at work and Penny's going to be a part of it—whether she wants to or not.

Cast: Johnny Galecki, Jim Parsons, Kaley Cuoco, Simon Helberg, Kunal Nayyar, Mayim Bialik, Melissa Rauch, Sean Astin, Chasty Ballesteros, Keili Lefkovitz, Joshua Malina, Kal Penn, Caleb Pierce