A girl drops off a sick baby at the ER and then leaves; Carter may get a kidney transplant; Gates and Daria care for an elderly woman with multiple sclerosis; Neela and Sam are in Seattle to transport a heart for Joanie Moore, while Doug and Carol are concerned that the donor's grandmother might not consent.

Cast: Noah Wyle, George Clooney, Julianna Margulies, Eriq La Salle, Parminder Nagra, John Stamos, Linda Cardellini, Scott Grimes, David Lyons, Angela Bassett, Susan Sarandon, Ernest Borgnine, Christian Clemenson, Hedy Burress, Yvette Freeman