Stem cells, gene therapy, transplants, cloning; The very meaning of the word \"humanity\" changes daily in the modern world. But there is a darker side to the evolution of mankind, a truth only a few brave souls are willing to face: There are monsters loose in the world. And they are the key to the future of our race.
Cast: Amanda Tapping, Robin Dunne, Ryan Robbins, Christopher Heyerdahl, Agam Darshi, Emilie Ullerup, Jonathon Young, Robert Lawrenson, Lynda Boyd, Chuck Campbell, Paul McGillion, Christine Chatelain, Sahar Biniaz, Mandy May, Callum Blue
SCIU has surrounded the 5th Ward with troops and an electric shield that prevents them from leaving. Caleb has a virus that can turn the human population into abnormals. Magnus enacts her ultimate plan for the Sanctuary network.
Seeking to outrace the SCIU (who are attempting to capture a rare, legendary Abnormal), Magnus and Will are captured, injured and trapped in a Bolivian cave-in. Alone, the two friends struggle to survive - as they confront who they are and who they've become.
Kate resurfaces with a warning about a Hollow Earth plot against an above-ground target, and evidence suggests that Bigfoot may be involved in the attack.
Adam Worth resurfaces as an avatar in a virtual Sanctuary, where he imperils Magnus and Tesla in a bid to enter the real world.
When a previously unknown Abnormal attacks Abby, Magnus and Will attempt to communicate with the creature using music - while Henry and Gavin retrace Abby's steps to find out what happened.
Team Sanctuary investigates a mystery on the high seas when the shipwrecked crew of a Bering Sea icebreaker murders the Abnormals on board and then turns on each other.
Will runs into unexpected trouble and personal revelations on a trip to the Liberian Sanctuary in Monorovia.
The team tracks an Abnormal fugitive, and discovers that Tesla is the head of a secret research lab for a Homeland Security agency that conducts tests on Abnormals.
Team Sanctuary comes under fire from a U.N. inspector who threatens to cut off their funding and shut them down - attempting to turn Will against Magnus in the process. Meanwhile, Erika visits Henry, warning him of a potentially dangerous new dilemma.
As Abnormals continue to "invade" the surface, Will, Kate and the Big Guy seek to prevent all-out war with the Lotus Security Forces - while worrying about Magnus, who was last seen heading towards Praxis just before it was destroyed.