When a botched U.S. government experiment turns a group of death row inmates into highly infectious vampires, an orphan girl might be the only person able to stop the ensuing crisis.
Cast: Brianne Howey, McKinley Belcher III, Brianna Brown, Caroline Chikezie, Emmanuelle Chriqui, Henry Ian Cusick, Mark-Paul Gosselaar, Jamie McShane, Vincent Piazza, Saniyya Sidney, Jason Fuchs
Following the explosion, surprising alliances are formed and a key figure returns to convince everyone to fight for their lives.
Amy must decide what's best for humanity when the only way to stop Fanning and the virals from escaping Project NOAH involves an explosion that could leave Brad, Sykes and the cure for the virus in the crossfire.
As Amy experiences symptoms of the virus that indicate she is close to turning, Brad brings everyone together, and Lila and Sykes race to perfect an anti-viral medicine to save her from Fanning.
Brad and Lila remember their history together as they plan to save Amy; Horace Guilder is given full authority over Project NOAH; Carter prepares Amy for Fanning's grand plan; Lear fights to help Elizabeth.
Guilder and Richards race to mobilize a search party when a viral gets loose outside Project NOAH; Amy creates friction with Brad when she volunteers to help in an unexpected way.
Brad and Amy plot their escape with an unlikely accomplice when a high ranking official suddenly arrives at Project NOAH; Sykes and Richards begin questioning each other's motives.
Wolgast convinces Sykes and Lear to let him and Amy outside of the facility for exercise in an effort to protect her; Fanning's hold on those kept in Project Noah grows stronger as flashbacks reveal how Carter wound up on death row.
Brad makes a deal with Sykes and Richards to stay with Amy at Project NOAH as they begin testing the virus on her, then forms an alliance when he discovers the truth about the state of the inmates in 4B; Babcock sheds light on her past.
Amy and a wounded Brad seek refuge with Brad's ex-military instructor; Dr. Lear reflects on the decisions that led him to involve Fanning in his research; testing of the virus on Anthony Carter begins.
As an imminent flu epidemic threatens the U.S., Federal Agent Brad Wolgast is tasked with bringing in the experiment's latest chosen test subject, a ten-year-old girl, Amy Bellafonte. But, after meeting Amy, Brad's loyalties to Project NOAH are tested.