When a failed alchemical ritual leaves brothers Edward and Alphonse Elric with severely damaged bodies, they begin searching for the one thing that can save them; the fabled philosopher's stone.
Cast: Aaron Dismuke, Vic Mignogna, Romi Pak, Rie Kugimiya, Tôru Ôkawa, Travis Willingham, Sonny Strait, Keiji Fujiwara, Takehiro Murozono, Kyle Hebert, Christopher Sabat, Kenji Utsumi, Shin Aomori, Jin Horikawa, Phil Parsons, Tetsu Shiratori, Kevin Connolly, Shouko Tsuda, Alex Sander, Geraldine Somerville, Steven Waddington, Perdita Weeks, James Wilby, Sophie Winkleman, Eszter Zakariás, Stephen Campbell Moore, Celia Imrie, Ralph Ineson, Peter Wight, Thomas Aldridge, Sally Bankes, Pandora Colin, Olivia Darnley, Joséphine de La Baume, David Eisner, Laurie Hagen, Ryan Hawley, Jonathan Howard, Mark Lewis Jones, Linda Kash, Christine Kavanagh, John Kazek, Grainne Keenan, Sylvestra Le Touzel, Joseph May, Simon Paisley Day, Miles Richardson, Sophie Rundle, Izabella Urbanowicz
As their journey draws to a close, the Elric brothers discover a new meaning for the Equivalent Exchange.
Ed battles Envy after returning from beyond the Gate; back at Central, Mustang takes on Pride.
Ed's confrontation with the leader of the homunculi leaves him with profound questions on the other side of the Gate.
Ed tries to rescue Al from the homunculi; Mustang has a radical strategy that may instigate a revolution.
A homunculi showdown is imminent when Sloth, Wrath and Lust all appear together.
The brothers become separated and find themselves in danger. Meanwhile, Al meets with an increasingly agitated Tucker, and Ed heads back to Dante's mansion to search for clues that could help him find the Homunculi's leader.
Hohenheim and the leader of the Homonculi continue to clash. Meanwhile, Col. Mustang challenges the military leadership by himself.
While attempting to elude capture, Ed and Al have to persuade Mustang's faction that the Fuhrer is a fraud.
Ed and Al take a perilous trip home after the philosopher's stone is created. The Fuhrer announces that the Elrics are fugitives, and he wants them dead or alive.
Scar plans to use Archer's soldiers to create the Philosopher's Stone; Lust follows Scar to try to discover the truth behind Scar's origin.
Ed tries to evacuate Liore before the alchemic reaction begins, but he is confronted by Wrath and Sloth; Scar, Kimbley and Al are embroiled in a climactic battle.
Marta finds Kimbley and wants revenge, but Al tries to intercede; Ed faces Scar and learns the truth about Ishbal's past; the identity of the Seventh Sin is revealed.
The chimera, Marta, leads Ed and Al to the ruins of Ishbal, and they are shocked by the devastation.
Ed and Al have a disagreement that sends them in opposite directions; Sciezka and Winry come face-to-face with a shape-shifting Sloth.
An investigation of Col. Mustang is ordered; a warehouse may be haunted by soldier-killing zombies.
Ed, Al and Winry travel to Ishbal, learning more about the terrible war that took place there.
In the aftermath of the battle with Greed, Lust questions her existence until a familiar figure from the past arrives
Major Armstrong fights Greed's men in an effort to save Al, while Ed faces a showdown with Greed himself.
The kidnappers take Al to their hideaway; Ed desperately tries to find his brother.
After a dangerous battle with Wrath, Izumi has all she can take of Ed and Al's reckless pursuit of their goal. She sends them to meet Dante, the alchemist who taught Izumi decades ago, and also knew their father. But there is little time for idle chat, as Envy, Sloth and Greed have all entered the vicinity.
In the chaos of the crumbling headquarters, Izumi successfully escapes with the boy. But it's too late-Envy has revealed the truth to the homunculus child, and his personality is quickly changing. With Izumi's secrets exposed as well, the Elric Brothers try to stop her heartbroken plan of atonement, converging on a cold stone altar on a lonely island.
The search for Scar gets a forward leap as a former military officer spots him in the southern slums. Elsewhere, the amoral Lt. Colonel Archer makes his move for the mysterious wild boy, who he believes is a homunculus conspirator. Infuriated by the arrest, Izumi leaps into action, single-handedly attacking the military with her staggering alchemic power.
As the Elric brothers are leaving Yock Island, a strange boy emerges from the foliage, with no memory of how he arrived. Inexplicably, he can perform alchemy without a transmutation circle. Even stranger, he can transmute his own body, merging with his surroundings! Izumi is compelled to take care of the child, but Ed has other plans.
It was the only clue Izumi offered, as she dumped young Ed and Al on the island of Yock: "One is All, All is One." It was perhaps the most ancient tenant of alchemy, but what did it mean? And how would it help these children survive in this savage place-with no food, no shelter, and a beast lurking in the woods? Years later, the lesson must be relearned.
Ever since Ed and Al attempted human transmutation, they have desperately avoided one person: their childhood teacher, Izumi. Bearing dreadlocks, an iron will, and incredible alchemic skills, she is horrified that Ed and Al used her teachings to violate nature. Now she has caught them, and is shipping them back to her hometown for a frightening interrogation.
Winry drags Ed and Al to the famous Rush Valley, the auto-mail capital of the world, where mechanical limbs are a shockingly common sight. Amidst workshops and street-smart swindlers, they encounter a tough girl named Paninya, who confronts Winry with an important question: Why is she helping Ed, if he doesn't even care?
Ed and Al claim they've quit their search for the Philosopher's Stone and board a train heading south. Meanwhile, Lieutenant Colonel Hughes' investigation of Lab Five leads him to a startling discovery of military corruption and conspiracy that could topple the entire national government-- and put Hughes in considerable danger.
As Al runs from Ed and Winry, desperate to know the truth about what he is, mercenaries swoop into the Ishbalan encampment where Scar is recovering and massacre helpless refugees-an attack the military may have condoned. In a chain of events, Al finds himself side by side with Scar, on a renegade mission against the state that Ed represents.
After the explosive finale to Lab Five, Ed and Al wake up in the hospital, once again in pieces. Winry travels to Central to make repairs, and is enraged by the brothers' refusal to tell her the truth about their lives. Meanwhile, Al's recurring questions about his existence come to a boil. Was there ever an Alphonse Elric? Or are his memories and soul alchemically created lies?
As Envy (in the form of Basque Grand) gathers the human ingredients to form the stone, Maes Hughes sets out to rescue the Elrics from laboratory 5.
Barry sets off explosions that inadvertently free the homonculus Greed and the other prisoners. Shou Tucker returns from the dead in a surprising new form.
Ed and Al square up against two guards that are just like Al; souls bound to armored suits. Ed however, may be in trouble as his auto mail malfunctions.
Ed and Al are horrified when they learn what the key ingredient in making a Philospher's stone is, but they forge ahead to explore an abandoned lab.
Ed and Al are forced to go in search of another source for Marcoh's books after Lust, Gluttony and Scar burn the first Branch Library to the ground.
The hobbled Elrics return to their childhood village for the first time in four years. As the Rockbells construct Ed's new limbs, the boys sift through the ashes they left behind. While Al comes to the fearful realization that his memories are fading, Ed visits his mother's grave, and both must redefine their view of family and home.
As Marcoh faces a deadly encounter with Lust, Armstrong and the Elrics flee to Resembool. Ed however, gets sent into a rage when they lose Al in the process.
As the Strong Arm Alchemist defends against the surrounding chaos, Marcoh reveals to the Elrics the vast atrocities of the Ishbal massacre.
While the shape-shifting Envy disguises himself as Cornello, Ed and Al find Marcoh and learn about the Stone's involvement in the Ishbal Rebellion.
Just in time for his annual Assessment, Ed challenges Mustang to a fight. If Ed wins, Roy must tell the truth about the traveling doctor who saved children in Xenotime.
Ed and Al uncover a conspiracy involving the Tringham brothers' father, his involvement with the red water and the disease that's stricken Xenotime.
The Elric brothers head to Xenotime in hopes of finding the Philosopher's Stone, but instead find two brothers who've stolen their identity and are poisoning the town with strange red water.
While trying to avoid their meeting with Mustang, Ed and Al end up in a small town and become embroiled in a manhunt for a female Robin Hood.
Ed and Al go on assignment to inspect a small mining colony and discover its inhabitants are being heavily taxed by a tyrannical military Lieutenant and his Alchemist.
A disheartened Ed resigns from his position as State Alchemist just as Winry arrives into town to visit. Winry however, may end up as the next victim of the city's serial killer.
Now an official state alchemist, Ed takes a closer look at Tucker's chimera experiments and begins to realize that something wrong has been going on.
Once in Central City, Ed and Al move into the vast mansion of the Sewing-Life Alchemist Shou Tucker and begin to prepare for the Alchemy exam.
The Elric brothers hop aboard a train to Central City and quickly find themselves defending the passengers -- including General Haruko -- from terrorists.
While on their way to seek out an important man from their childhood, Ed and Al come across a town haunted by a ghostly woman.
A young Ed and Al are determined to bring back their dead mother, who was their pillar of strength in light of their absent father and war struck country.
Knowing the truth behind the prophet's power, the Elrics seek to unseat him and reveal the truth to the citizens of that desert city. They also seek to steal the source of the power for themselves, until they discover a secret about it that even the prophet didn't know.
A lead on the Philosopher's Stone leads the Elric brothers to a remote desert city whose citizens worship a sun god and are led by a prophet who is purported to perform miracles.