Peter Parker is beset with troubles in his failing personal life as he battles a brilliant scientist named Doctor Otto Octavius, who becomes Doctor Octopus (aka Doc Ock), after an accident causes him to bond psychically with mechanical tentacles that do his bidding.

Director: Sam Raimi

Cast: Tobey Maguire, Kirsten Dunst, James Franco, Alfred Molina, Rosemary Harris, J.K. Simmons, Donna Murphy, Daniel Gillies, Dylan Baker, Bill Nunn, Vanessa Ferlito, Aasif Mandvi, Willem Dafoe, Cliff Robertson, Ted Raimi