The hopes and dreams of four ambitious people are shattered when their drug addictions begin spiraling out of control.

Director: Darren Aronofsky

Cast: Ellen Burstyn, Jared Leto, Jennifer Connelly, Marlon Wayans, Christopher McDonald, Louise Lasser, Marcia Jean Kurtz, Janet Sarno, Suzanne Shepherd, Joanne Gordon, Charlotte Aronofsky, Mark Margolis, Michael Kaycheck, Jack O\'Connell, Chas Mastin